BioPETsurv: Biomarker Prognostic Enrichment Tool for Time-to-Event Trial
Prognostic Enrichment is a strategy of enriching a clinical trial for testing an intervention intended to prevent or delay an unwanted clinical event. A prognostically enriched trial enrolls only patients who are more likely to experience the unwanted clinical event than the broader patient population (R. Temple (2010) <doi:10.1038/clpt.2010.233>). By testing the intervention in an enriched study population, the trial may be adequately powered with a smaller sample size, which can have both practical and ethical advantages.
This package provides tools to evaluate biomarkers for prognostic enrichment of clinical trials with survival/time-to-event outcomes.
||R (≥ 3.1.0)
||survival, ggplot2, gridExtra
||Si Cheng [cre, aut],
Kathleen F. Kerr [ctb]
||Si Cheng <chengsi at uw.edu>
||GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
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