Variations of Remove Unwanted Variation-III (RUV-III) known as RUV-III-C (RUV-III Complete). RUV-III performs normalisation using negative control variables and replication. RUV-III-C extends this method to cases where the data contains missing values, by applying RUV-III to complete subsets of the data. Originally designed for SWATH-MS proteomics datasets. Poulos et al. (2020) <doi:10.1038/s41467-020-17641-3>.

Version: 1.0.19
Depends: R (≥ 3.5), RSpectra, progress
LinkingTo: Rcpp, RcppEigen, RSpectra, RcppProgress
Suggests: ruv, testthat
Published: 2021-04-23
Author: Rohan Shah [aut, cre], Sean Peters [ctb], Qing Zhong [ctb], Children's Medical Research Institute [cph]
Maintainer: Rohan Shah <rshah at>
License: MIT + file LICENSE
NeedsCompilation: yes
SystemRequirements: C++11
In views: Omics
CRAN checks: RUVIIIC results


Reference manual: RUVIIIC.pdf


Package source: RUVIIIC_1.0.19.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): RUVIIIC_1.0.19.tgz, r-oldrel (arm64): RUVIIIC_1.0.19.tgz, r-release (x86_64): RUVIIIC_1.0.19.tgz, r-oldrel (x86_64): RUVIIIC_1.0.19.tgz
Old sources: RUVIIIC archive


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