replicateBE: Average Bioequivalence with Expanding Limits (ABEL)

Performs comparative bioavailability-calculations for the EMA's Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' and 'Method B', detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence (ABE) - optionally with tighter (EMA: NTIDs) or wider limits (GCC: Cmax) - is implemented as well.

Version: 1.0.11
Depends: R (≥ 3.5.0)
Imports: readxl (≥ 1.0.0), PowerTOST (≥ 1.3.3), lmerTest, nlme, pbkrtest, graphics, grDevices
Suggests: knitr, rmarkdown, testthat, devtools
Published: 2019-08-25
Author: Helmut Schütz ORCID iD [aut, cre], Michael Tomashevskiy [ctb], Detlew Labes ORCID iD [ctb]
Maintainer: Helmut Schütz <helmut.schuetz at bebac.at>
BugReports: https://github.com/Helmut01/replicateBE/issues
License: GPL (≥ 3)
URL: https://github.com/Helmut01/replicateBE
NeedsCompilation: no
Materials: README NEWS
CRAN checks: replicateBE results

Downloads:

Reference manual: replicateBE.pdf
Vignettes: replicateBE
Package source: replicateBE_1.0.11.tar.gz
Windows binaries: r-devel: replicateBE_1.0.10.zip, r-release: replicateBE_1.0.10.zip, r-oldrel: replicateBE_1.0.10.zip
OS X binaries: r-release: replicateBE_1.0.10.tgz, r-oldrel: replicateBE_1.0.10.tgz
Old sources: replicateBE archive

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