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geneSLOPE – Genome Wide Association Study with SLOPE

Package geneSLOPE can be used to perform Genome-wide association study with SLOPE.

Such an analysis is split into three steps.

  1. Data is read and immediately screened using a marginal test for each SNP.
  2. SNPs are clumped based on correlations.
  3. SLOPE is performed on reduced data. Each clump is represented by one SNP.

How do I get set up?

You can install the latest development version of the code using the devtools R package.

# Install devtools, if you haven't already.
install.packages("devtools")

library(devtools)
install_github("psobczyk/geneSLOPE")

Running GUI

GUI based on shiny R package is available

library(geneSLOPE)
gui_geneSLOPE()

Who do I talk to?


Research reported in this software was supported by National Institutes of Health under award number R01 HG006695.


This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 602552.